Your Gut Is Talking to Your Hormones: The Menopause Microbiome Connection

The Menopause Mastery Show | Your Gut Is Talking to Your Hormones: The Menopause Microbiome Connection  | Ep. 295 with Dr. Eddie Romo

🌿Welcome to The Menopause Mastery Show!

👉 What if your gut microbiome is influencing far more than digestion? In this episode of Menopause Mastery, Dr. Betty Murray sits down with microbiologist Dr. Eddie Romo, to explore the powerful connection between the gut microbiome, estrogen metabolism, menopause, inflammation, and brain health.

Dr. Romo explains why the microbiome should be viewed as an active metabolic ecosystem—not simply a collection of "good" and "bad" bacteria. They discuss the estrobolome, the role gut bacteria play in estrogen recycling, and why changes in estrogen during perimenopause and menopause can also change the microbiome.

The conversation also challenges the idea that probiotics are a universal solution. Dr. Romo explains why personalized, longitudinal microbiome testing may provide a much clearer picture than a single snapshot, and why factors like diet, sleep, exercise, stress, hormones, fiber, fermented foods, and polyphenols all matter.

They also explore the emerging relationship between the gut and Alzheimer's risk, systemic inflammation, the blood-brain barrier, hormone replacement therapy, and women's health—and discuss the future of more personalized microbiome and hormone testing.

☑️ Your gut microbiome is an active part of your biology—not a passive collection of bacteria. Supporting a healthy, diverse gut ecosystem may be an important piece of protecting hormonal balance, metabolic health, and brain function throughout menopause and beyond!

🔗 To connect with Dr. Romo:

https://www.instagram.com/dr.eddieromo

https://www.phbio.ai/

00:00:00 — Introduction: Menopause, Hormones & the Microbiome

00:01:27 — Dr. Eddie Romo's Journey Into Microbiology