Episode 157: Could Creatine Support Energy and Cognitive Function in Long Covid?

Creatine is often associated with the fitness industry and sports performance — but emerging research is now exploring whether it may have relevance far beyond the gym.

In this episode, Anna explores the current evidence surrounding creatine supplementation in Long Covid and fatigue-related conditions, including its potential role in energy metabolism, muscle function, cognitive symptoms, nervous system health, and recovery capacity.

This conversation also looks at:

Why creatine is being investigated in Long Covid

The link between ATP production and fatigue

Potential neuroprotective and antioxidant mechanisms

Brain fog and cognitive symptoms

Muscle weakness, PEM, and pacing considerations

Why individual responses to supplements can vary

Considerations around dosage, safety, and supplement sensitivity

Creatine and the menstrual cycle

Importantly, this episode takes a balanced and non-dogmatic approach. While early research is promising, creatine is not presented as a “magic bullet” or standalone solution for Long Covid.