JAMA Cardiology October 2026 Global, Regional, and National Burden of Heart Failure, 1990-2023 A Systematic Analysis for the Global Burden of Disease Study 2023

A recent cross-sectional analysis utilizing Global Burden of Disease methodologies evaluates the worldwide impact and underlying causes of heart failure across 204 countries and territories from 1990 to 2023. By synthesizing extensive data, the research revealed an estimated 56.0 million cases globally in 2023, with prevalence rates consistently rising alongside advancing age. The study highlights that specific causes vary dramatically depending on geographic region and age group, noting issues like ischemic and hypertensive heart disease in older populations alongside congenital, rheumatic, and alcohol-related conditions in younger cohorts. Because heart failure represents a growing global health challenge, targeting modifiable risk factors such as high blood pressure and excessive drinking remains crucial. Ultimately, these region-specific findings equip public health leaders with vital insights to design targeted interventions and effectively reduce disease burdens worldwide