Dr. Colleen Cutcliffe, PhD: Natural GLP-1 Production, Fiber Deficiency, Akkermansia and the Gut Microbiome Connection

<p>Most people think of the gut as a digestive organ. It is not. It is the upstream controller of your metabolism, immune function, brain health, skin, and hormones and almost everyone is running it on a depleted, misfed microbiome without knowing it.</p><p>Dr. Colleen Cutcliffe, PhD is the co-founder and CEO of Pendulum Therapeutics, holds a PhD in biochemistry from Johns Hopkins, and spent over 15 years in pharma and biotech before pioneering next-generation probiotic science. Her team was the first in the world to manufacture Akkermansia, a strain found at high levels in virtually every centenarian population studied and depleted in almost every major chronic disease. </p><p>What makes this conversation different from most gut health discussions is the level of scientific rigor behind it. This is not wellness theory. This is published research, clinical data, and a decade of actually building the science from the ground up.</p><p>Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&amp;As, the latest female longevity science, and a private, supportive community of like-minded women.</p><p><a href="https://kayla-barnes-lentz.circle.so/checkout/become-a-member"><u>https://kayla-barnes-lentz.circle.so/checkout/become-a-member</u></a></p><p><strong>In this conversation we explore:</strong></p><ul><li><p>How your gut produces its own GLP-1 naturally and why synthetic versions may blunt that system over time</p></li><li><p>Why Akkermansia is elevated in centenarians and depleted across virtually every chronic disease</p></li><li><p>The fiber gap: 95% of people are under-threshold and it is driving metabolic and colon health decline</p></li><li><p>What early antibiotic use does to the microbiome and how to rebuild at any age</p></li><li><p>Why soap may be fueling the allergy and asthma epidemic by stripping the skin&#39;s protective barrier</p></li><li><p>How butyrate links gut health, colon cancer risk, and natural GLP-1 production</p></li><li><p>Why most probiotics on Amazon do not contain what the label claims</p></li></ul><p><strong>Connect with Kayla:</strong></p><p>Instagram:<a href="https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbV9UTElwSGJwV243ZGFzS2Y4NGxWc3B6X2lZZ3x